We are interested in using a variety of methods to estimate free energy changes in various biological phenomena.

HEME transfer

Hb to NEAT domain HEME transfer

TRPV6 channel

Calcium Ion Channel

AMPA receptor dynamical allostery and gating mechanisms

Gating and mechanisms of channel activation and deactivation

NMDA receptor transmembrane domain structure and function

Mechanism of divalent ion selectivity - Mechanism of transmembrane domain (TMD) pore opening