Welcome to Kurnikova Research Group


 Our group specializes in theoretical computational modeling of structure-function relationships in biological macromolecules, such as proteins, lipids and RNA. 

 Position Open: 

 Applications are invited for a postdoctoral position in Professor Maria Kurnikova's group at Carnegie Mellon University to develop and apply computational approaches to study various aspects of glutamate receptor functioning and drug interaction, non-heme metal protein catalysts, computational drug design. The position is funded by grants from NIH and NSF and is available immediately. The initial appointment will be for 1 year with possible extension upon mutual agreement. The salary is generous at NIH level of postdoctoral fellowships.

All projects in my group will require versatile application of multiple methods of computational chemistry and molecular modeling as well as development of new methodological approaches and software. The successful candidate will have extensive experience in modern advanced methods of molecular modelling and simulations, deep understanding of statistical mechanics and will hold a PhD in physics, chemistry, quantitative biology, applied mathematics, or a closely related field, with a strong interest in biological systems. Experience with membrane associated proteins and ion channels, or free energy methods is a plus. 

To apply please send your cover letter, CV and two-three names for your reference letters via email to kurnikova at cmu.edu




HEME transfer

Hb to NEAT domain HEME transfer

TRPV6 channel

Calcium Ion Channel

AMPA receptor dynamical allostery and gating mechanisms

Gating and mechanisms of channel activation and deactivation

NMDA receptor transmembrane domain structure and function

Mechanism of divalent ion selectivity - Mechanism of transmembrane domain (TMD) pore opening